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Creatinine wordt veel gebruikt in de diergeneeskunde om de nierfunctie te evalueren. Toch heeft het belangrijke beperkingen. Dit late marker stijgt namelijk pas wanneer al 75% van de nierfunctie verloren is, waardoor de diagnose wordt vertraagd. Bovendien kunnen andere factoren, zoals de spiermassa, vooral bij senior dieren, de resultaten beïnvloeden.
In deze 2ᵉ aflevering van onze serie ""Het advies van de specialist - Nieuwigheden over de gezondheid van de nier ?" zal Dr. Sylvie Daminet de beperkingen van creatinine als niermarker onderzoeken en nieuwe alternatieven presenteren, zoals SDMA en, meer recent, FGF23, een marker voor metabole verstoring, die een vroegere detectie van nierziekten mogelijk maakt.
Sylvie Daminet graduated in 1992 from the University of Liège in Belgium. Thereafter she performed an internship followed by a residency in Internal Medicine at the University of Montreal in Canada. In 1996 she became a diplomate of the American College of Veterinary Internal Medicine and of the European College of Veterinary Internal Medicine (ACVIM & ECVIM).
She was an assistant Professor at the Universities of Montreal and Prince Edward Island in Canada and Lecturer at the Royal Veterinary College in London (England). She obtained her PhD on thyroid function tests in dogs at the University of Ghent in Belgium in 2002. Currently she is a full Professor at the same University. She is chair of the small animal internal medicine service and her clinical and research interest are in endocrinology and nephrology.
Sylvie (co)-authored approximately 150 publications in international and national journals. She was president of the European Society of Veterinary Endocrinology (2009-2011) and chair of the Specialty of Internal Medicine of ECVIM (2011-2014).
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